7116073
CID 16020046
Selective GPR55 antagonist
Manufacturer: Fischer Scientific
CAS Number: 834903-43-4
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Chemical Name or Material
4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid
Assay Percent Range
>99%
Formula Weight
Observed MW: 425.44
CAS
834903-43-4
Molecular Formula
C25H19N3O4
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
CID 16020046 | -- | ₹ 63,190.00 | ||
CID 16020046 | -- | ₹ 16,874.40 |
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Description
- Selective GPR55 antagonist
- Inhibits LPI-induced Ca2+ signaling (IC50 = 0.21 μM in HEK-GPR55 cells), ERK1/2 phosphorylation and GPR55-mediated transcription factor activation
- Displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG
- Decreases LPI-induced GPR55 internalization
- Reduces experimental intestinal inflammation in mice.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C