7121039
Tocris Bioscience™ Galeterone
CYP17 inhibitor; also androgen receptor antagonist
Manufacturer: Fischer Scientific
CAS Number: 851983-85-2
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Chemical Name or Material
Galeterone
Synonym
(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol
Molecular Formula
C26H32N2O
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
851983-85-2
Solubility
Soluble to 50mM in DMSO and to 50mM in ethanol
Formula Weight
388.55
Color
White
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Galeterone | -- | ₹ 84,906.00 | ||
Tocris Bioscience™ Galeterone | -- | ₹ 21,004.00 | ||
Sigma Aldrich Fine Chemicals Biosciences Galeterone >=98% (HPLC) | 851983-85-2 | MFCD16660907 | 5MG | -- | ₹ 10,302.64 | ||
Sigma Aldrich Fine Chemicals Biosciences Galeterone >=98% (HPLC) | 851983-85-2 | MFCD16660907 | 25MG | -- | ₹ 39,467.05 |
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Description
- CYP17 inhibitor (IC50 = 300 nM) and androgen receptor antagonist (IC50 = 384 nM in PC3-AR cells)
- Inhibits DHT-stimulated prostate cancer cell proliferation in vitro
- Exhibits antitumor activity in SCID mice bearing prostate cancer xenografts.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C