7182923

Tocris Bioscience™ GSK 2239633A

Potent CCR4 antagonist

Manufacturer: Fischer Scientific

CAS Number: 1240516-71-5

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Chemical Name or Material

N-[[3-[[3-[[(5-Chloro-2-thienyl)sulfonyl]amino]-4-methoxy-1H-indazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide

CAS

1240516-71-5

Molecular Formula

C24H25ClN4O5S2

Purity

98%

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Description

  • Potent CCR4 antagonist (pIC50 = 7.83 in a 35S-GTPγS competition assay)
  • Inhibits thymus activation-regulated chemokine (TARC) -induced F-actin polymerization in human whole blood.