7199091

Tocris™ RO 5263397 hydrochloride

Potent TA1 receptor agonist

Manufacturer: Fischer Scientific

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Chemical Name or Material

(4S)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamine hydrochloride

Target

Trace Amine 1 (TA1) Receptor Agonists

Molecular Formula

C10H11FN2O.HCl

Purity

98%

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Description

  • Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively)
  • Increases wakefulness and reduces REM and NREM sleep duration in wild type mice
  • Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C