7199100
Tocris™ Dynapyrazole A
Hedgehog signaling inhibitor; dynein inhibitor
Manufacturer: Fischer Scientific
CAS Number: 2226517-75-3
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Chemical Name or Material
2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Target
Hedgehog Signaling Inhibitors
Purity
98%
CAS
2226517-75-3
Molecular Formula
C20H12ClIN4O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris™ Dynapyrazole A | -- | ₹ 39,437.68 | ||
Tocris™ Dynapyrazole A | -- | ₹ 10,220.76 | ||
eMolecules Medchem Express / Dynapyrazole-A / 5mg / 783660457 / HY-131873 / / 2226517-75-3 / [null] / 486.700 / C20H12ClIN4O | -- | ₹ 11,790.72 | ||
Dynapyrazole A | -- | ₹ 14,418.00 - ₹ 91,136.00 | ||
2226517-75-3 | Dynapyrazole A | -- | ₹ 6,230.00 - ₹ 35,956.00 |
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Description
- Dynein inhibitor
- Inhibits dynein 1 and dynein 2-dependent microtubule gliding (IC50 values are 2.3 and 2.6 μM, respectively)
- Inhibits hedgehog signaling in vitro (IC50 = 1.9 μM)
- Displays reversible inhibition of retrograde and anterograde intraflagellar transport in Chlamydomonas ; displays stronger inhibition of retrograde transport.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C