72-802-5

Tocris™ GRL 0617

Manufacturer: Tocris™

CAS Number: 1093070-16-6

Select a Size

Pack Size SKU Availability Price
Each of 1 72-802-5-Each-of-1 In Stock ₹ 79,477.00

72-802-5 - Each of 1

₹ 79,477.00

In Stock

Quantity

1

Base Price: ₹ 79,477.00

GST (18%): ₹ 14,305.86

Total Price: ₹ 93,782.86

Chemical Name or Material

5-Amino-2-methyl-N-[(1 R)-1-(1-naphthalenyl)ethyl]benzamide

Quantity

25 mg

Molecular Formula

C20H20N2O

CAS

1093070-16-6

Target

Papain-like Protease Inhibitors

Purity

0.98

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Description

  • Description GRL 0617 is a coronavirus papain-like protease (Plpro) inhibitor (IC50 values are 0.6 and 0.8 μM for SARS-COV and SARS-CoV-2 PLpro, respectively)
  • Inhibits deubiquitination activity of SARS-CoV PLpro
  • Displays no inhibition of human deubiquitinating enzymes
  • Improves cell viability following SARS-CoV infection
  • Inhibits SARS-CoV-2 viral replication and induces antiviral immune signaling pathways following SARS-CoV-2 infection in CaCo-2 cells.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C