7237107
Tocris Bioscience™ Nimbolide
RNF114 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 25990-37-8
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Chemical Name or Material
(2 aR,5 aR,6 S,6 aR,8 R,9 aR,10 AS,10 bR,10 cR)-8-(3-Furanyl)-2 A,5 A,6,6 A,8,9,9 A,10 A,10 b,10 c-decahydro-2 A,5 A,6 A,7-tetramethyl-2,5-dioxo-2 H,5 H-cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid methyl ester
Target
Ubiquitin Ligase (E3) Inhibitors
Purity
0.97
CAS
25990-37-8
Molecular Formula
C27H30O7
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ Nimbolide | -- | ₹ 1,34,123.00 | ||
Tocris Bioscience™ Nimbolide | -- | ₹ 32,129.00 | ||
eMolecules Medchem Express / Nimbolide / 5mg / 599423733 / HY-116035 / / 25990-37-8 / [null] / 466.530 / C27H30O7 | -- | ₹ 36,682.24 | ||
Medchemexpress LLC HY-116035 5mg , Nimbolide CAS:25990-37-8 Purity:>98% | -- | ₹ 26,166.00 | ||
Nimbolide | -- | ₹ 1,69,627.75 | ||
Nimbolide | -- | ₹ 38,807.63 | ||
25990-37-8 | Nimbolide | -- | ₹ 20,114.00 - ₹ 84,817.00 |
Related Products
Description
- Nimbolide inhibits auto-ubiquitination of the E3 ligase RNF114 and p21 ubiquitination in vitro
- This compound impairs proliferation of triple-negative breast cancer cell lines
- Nimbolide also induces apoptotic cell death in a Waldenströms macroglobulinemia cell line (BCWM1) and inhibits tumor growth in a xenograft model of Waldenströms macroglobulinemia
- Nimbolide can be used for the development of Degraders that utilize RNF114 as an E3 ligase for Targeted Protein Degradation.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C