7237112

Tocris Bioscience™ K 22

Inhibits coronavirus RNA replication; impairs double membrane vesicle (DMV) formation

Manufacturer: Fischer Scientific

CAS Number: 2141978-86-9

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Chemical Name or Material

N-[(1 Z)-1-[[4-(4-Bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]benzamide

Target

DNA, RNA and Protein Synthesis Inhibitors

Purity

0.98

CAS

2141978-86-9

Molecular Formula

C27H25BrN2O3

Other Options

Image Product Name Manufacturer Price Range
Tocris Bioscience™ K 22
-- ₹ 16,473.90
Tocris Bioscience™ K 22
-- ₹ 68,530.00
K22
-- --

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Description

  • K 22 is a viral RNA synthesis inhibitor; targets membrane-bound coronaviral RNA replication by inhibiting double membrane vesicle (DMV) formation
  • Inhibits HCoV-229E infection of MRC-5 cells in a plaque forming assay (IC50 = 0.7 μM)
  • Also inhibits HCoV-229E and MERS-CoV replication in human airway epithelia cultures.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C