74-145-0

Tocris Bioscience™ DSRM-3716

Manufacturer: Tocris Bioscience™

CAS Number: 58142-99-7

Select a Size

Pack Size SKU Availability Price
Each of 1 74-145-0-Each-of-1 In Stock ₹ 24,831.00

74-145-0 - Each of 1

₹ 24,831.00

In Stock

Quantity

1

Base Price: ₹ 24,831.00

GST (18%): ₹ 4,469.58

Total Price: ₹ 29,300.58

Chemical Name or Material

5-Iodoisoquinoline

Quantity

50 mg

Molecular Formula

C9H6IN

CAS

58142-99-7

Target

Hydrolase Inhibitors

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
Medchemexpress LLC HY-W021879 50mg , DSRM-3716 CAS:58142-99-7 Purity:>98%
-- ₹ 5,139.75
eMolecules​ 5-Iodoisoquinoline | 58142-99-7 | MFCD11226893 | 1g
-- ₹ 3,880.40
Isoquinoline, 5-iodo- (9CI)
-- ₹ 445.00 - ₹ 32,218.00
DSRM-3716
-- ₹ 1,246.00 - ₹ 43,254.00
58142-99-7 | 5-Iodoisoquinoline
-- ₹ 1,246.00 - ₹ 43,254.00

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Description

  • DSRM-3716 is a potent, reversible inhibitor of SARM1 NAD(+) hydrolase (IC50 = 75 nM), which displays selectivity for SARM1 over related enzymes NAMPT and NMNAT and a panel of receptors and transporters
  • In vitro , DSRM-3716 decreases cyclic adenosine diphosphate ribose (cADPR) levels in mouse dorsal root ganglia (DRG) neurons, and protects mouse DRG and iPSC-derived human motor neurons against axonal degeneration
  • In axons with rotenone (Cat
  • No
  • 3616)-induced mitochondrial injury, DSRM-3716 rescues axons displaying indicators of degeneration.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C