78-505-0
Tocris Bioscience™ MK 2206 dihydrochloride
Manufacturer: Fischer Scientific
CAS Number: 1032350-13-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 78-505-0-Each-of-1 | In Stock | ₹ 52,065.00 |
78-505-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,065.00
GST (18%): ₹ 9,371.70
Total Price: ₹ 61,436.70
Chemical Name or Material
8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride
Quantity
50 mg
Molecular Formula
C25H21N5O.2HCl
CAS
1032350-13-2
Target
Akt (Protein Kinase B) Inhibitors
Purity
0.98
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ MK 2206 dihydrochloride | -- | -- | ||
Tocris Bioscience™ MK 2206 dihydrochloride | -- | ₹ 12,379.90 | ||
Medchemexpress LLC HY-10358 200mg , MK-2206 (dihydrochloride) CAS:1032350-13-2 Purity:>98% | -- | ₹ 42,052.50 | ||
Apexbio Technology LLC MK-2206 dihydrochloride, 500mg. Cas: 1032350-13-2 MFCD: MFCD14584463. Akt1/2/3 inhibitor | -- | ₹ 1,33,500.00 | ||
Medchemexpress LLC 10 mM * 1 mL in DMSO, MK2206 | 1032350-13-2 | -- | ₹ 6,167.70 | ||
Selleck Chemical LLC MK-2206 2HCl 5mg 1032350-13-2 | -- | ₹ 15,699.60 | ||
Selleck Chemical LLC MK-2206 2HCl 25mg 1032350-13-2 | -- | ₹ 42,399.60 | ||
AdipoGen MK-2206 dihydrochloride, 1032350-13-2, MFCD14584463, 1 mg | -- | ₹ 7,778.60 | ||
Cayman Chemical MK-2206 (hydrochloride), 1032350-13-2, 10 mg | -- | ₹ 10,849.10 | ||
Cayman Chemical MK-2206 (hydrochloride), 1032350-13-2, 1 mg | -- | ₹ 4,663.60 |
Related Products
Description
- MK 2206 dihydrochloride is a potent and selective allosteric Akt inhibitor (IC50 values are 5 nM, 12 nM, and 65 nM for Akt1, Akt2, and Akt3, respectively)
- MK 2206 requires the Pleckstrin homology domain for its activity, and exhibits no inhibitory activity in a panel of 250 tested protein kinases
- MK 2206 induces growth inhibition of different cancer cell lines (IC50 in the range 3.4 and 28.6 μmol/L) and enhances antitumor efficacy of a range of standard chemotherapeutics
- It synergistically inhibits cell proliferation of human lung and breast cancer cells in combination with Erlotinib (Cat
- No
- 7194) by suppressing both the Ras/Erk and PI 3-K pathways in vitro and in vivo
- MK 2206 can be used to block the IL-22 - Akt signaling pathway for studying paneth cell differentiation.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C