4530976
Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)
Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.
Manufacturer: Fischer Scientific
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Cleavable
No
Molecular Weight (g/mol)
572.43
PEGylated
No
Solubility
Water
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Description
- Thermo Scientific™ Pierce BS3 (Sulfo-DSS) is bis(sulfosuccinimidyl)suberate, an amine-to-amine crosslinker that is homobifunctional, water-soluble, non-cleavable and membrane impermeable
- Highlights: Crosslink cell-surface proteins before cell lysis and immunoprecipitation Identify receptor-ligand interactions by chemical crosslinking “Fix” protein interactions to allow identification of weak or transient protein interactions Identify near-neighbor protein interactions Protein crosslinking to create bioconjugates via single-step reactions Immobilize proteins onto amine-coated surfaces