16-141-0
SB 431542, Tocris Bioscience™
Manufacturer: Fischer Scientific
CAS Number: 301836-41-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 16-141-0-Each-of-1 | In Stock | ₹ 41,207.00 |
16-141-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,207.00
GST (18%): ₹ 7,417.26
Total Price: ₹ 48,624.26
Chemical Name or Material
SB 431542
Synonym
4-4-2h-1,3-benzodioxol-5-yl-5-pyridin-2-yl-1h-imidazol-2-yl benzamide
Molecular Formula
C22H16N4O3
CAS
301836-41-9
Quantity
10 mg
Formula Weight
384.39
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
SB 431542, Tocris Bioscience™ | -- | -- | ||
SB 431542, Tocris Bioscience™ | -- | ₹ 19,313.00 | ||
Medchemexpress LLC HY-10431 50mg , SB-431542 CAS:301836-41-9 Purity:>98% | -- | ₹ 33,642.00 | ||
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor VI, SB431542 | -- | ₹ 17,212.60 | ||
eMolecules SB-431542 | 301836-41-9 | MFCD05865244 | 50mg | -- | ₹ 14,410.88 | ||
Selleck Chemical LLC SB431542 10mg 301836-41-9 | -- | ₹ 21,039.60 | ||
Medchemexpress LLC SB-431542 | 301836-41-9 | MFCD05865244 | 10mg | -- | ₹ 8,971.20 | ||
Sigma Aldrich Fine Chemicals Biosciences SB 431542 hydrate | 301836-41-9 | MFCD11045982 | 5 mg | -- | ₹ 20,932.80 | ||
Apexbio Technology LLC SB 431542, 301836-41-9, MFCD05865244, 10 mg | -- | ₹ 6,853.00 | ||
Selleck Chemical LLC SB431542 50mg 301836-41-9 | -- | ₹ 79,494.80 |
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Description
- Description SB 431542 is a potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor/ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7
- Suppresses TGF-β-induced proliferation of human osteosarcoma cells
- Replaces SOX2 in reprogramming of fibroblasts into iPSCs
- Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells
- Inhibits TGF-β-induced EMT, migration, invasion and VEGF secretion in several human cancer cell lines
- SB 431542 synthesized to cGMP guidelines also available
- For more information about how SB 431542 may be used, see our protocols: 3D Culture of Lung Alveolar Cells, Differentiation of Hematopoietic Progenitors from hPSCs, Generating Midbrain Dopaminergic Neurons from hPSCs, Generating Vascular Organoids, Accelerated Induction of Cortical Neurons from hiPSCs .
SAFETY INFORMATION
- Recommended Storage : Store at Room Temperature