20-872-5100UG
MilliporeSigma™ Calbiochem™ Calphostin C, Cladosporium cladosporioides
Manufacturer: Fischer Scientific
CAS Number: 121263-19-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 20-872-5100UG-Each-of-1 | In Stock | ₹ 25,009.00 |
20-872-5100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,009.00
GST (18%): ₹ 4,501.62
Total Price: ₹ 29,510.62
Color
Light Brown
CAS
121263-19-2
Formula Weight
790.8g/mol
Content And Storage
Protect from light
Quantity
100 μg
Target Proteins
PKC
Molecular Formula
C44H38O14
Solubility
DMSO or EtOH
Form
Lyophilized
Purity
95% by HPLC
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
MilliporeSigma™ Calbiochem™ Calphostin C, Cladosporium cladosporioides | -- | -- | ||
MilliporeSigma™ Calbiochem™ Calphostin C, Cladosporium cladosporioides | -- | -- | ||
Enzo Life Sciences Calphostin C (100µg). CAS: 121263-19-2 | -- | ₹ 14,840.75 | ||
Calphostin C | -- | ₹ 46,280.00 | ||
121263-19-2 | Carbonic acid,(1R)-2-[12-[(2R)-2-(benzoyloxy)propyl]-3,10-dihydro-4,9-dihydroxy-2,6,7,11-tetramethoxy-3,10-dioxo-1-perylenyl]-1-methylethyl4-hydroxyphenyl ester, stereoisomer | -- | ₹ 1,32,610.00 |
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Description
- A cell permeable, highly specific inhibitor of protein kinase C (IC 50 = 50nM) that interacts with the protein’s regulatory domain by competing at the binding site of diacylglycerol and phorbol esters
- Does not compete with Ca 2+ or phospholipids
- At higher concentrations inhibits myosin light chain kinase (IC 50 > 5μM), protein kinase A (IC 50 > 50μM), protein kinase G (IC 50 > 25μM), and p60 v- src (IC 50 > 50μM)
- Induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells
- Requires brief exposure to light for activation.