50-051-10001

MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Inhibitor VIII, NU9056

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-051-10001-Each-of-1 In Stock ₹ 24,423.38

50-051-10001 - Each of 1

₹ 24,423.38

In Stock

Quantity

1

Base Price: ₹ 24,423.38

GST (18%): ₹ 4,396.208

Total Price: ₹ 28,819.588

Color

Yellowish Brown

Target Proteins

KAT5

Solubility

DMSO

Form

Oil

Description

97% by HPLC

Molecular Formula

C6H4N2S4

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable disulfane compound that is reported to be more potent against KAT5/Tip60 than PCAF, p300, and GCN5 in cell-free HAT activity assays (IC 50 ≤2, ≤36, ≤60, and >100μM, respectively) and effectively reduce H3K14, H4K8, H4K16, but not α-tubulin, acetylation level in LNCaP prostate cancer cells (max inhibition at 5-10μM)
  • Shown to induce cell cycle arrest and apoptosis (17 to 24μM) in LNCaP cultures and exhibit antiproliferation activity in both androgen-responsive and androgen-independent CaP cultures (GI 50 from 7.5 to 27μM)
  • Please note that the molecular weight for this compound is batch-specific due to variable water content
  • Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight
  • The molecular weight provided represents the baseline molecular weight without water.