55-744-0500UG

MilliporeSigma™ Calbiochem™ Ru360

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 55-744-0500UG-Each-of-1 In Stock ₹ 28,821.76

55-744-0500UG - Each of 1

₹ 28,821.76

In Stock

Quantity

1

Base Price: ₹ 28,821.76

GST (18%): ₹ 5,187.917

Total Price: ₹ 34,009.677

Color

Reddish Brown

Molecular Formula

C2H26Cl3N8O5Ru2

Solubility

deoxygenated H2O

Form

Solid

Purity

97% by capillary electrophoresis

Target Proteins

Ca2+ uptake into mitochondria in vitro

Formula Weight

550.8g/mol

Content And Storage

Hygroscopic, Protect from light

Quantity

500 μg

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Description

  • A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM)
  • Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min)
  • Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.