68-167-22MG
MilliporeSigma™ Calbiochem™ Wnt/β-catenin Inhibitor, Cardamonin
Manufacturer: MilliporeSigma™
CAS Number: 19309-14-9
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 68-167-22MG-Each-of-1 | In Stock | ₹ 16,668.81 |
68-167-22MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,668.81
GST (18%): ₹ 3,000.386
Total Price: ₹ 19,669.196
Color
Orange-yellow to Amber
CAS
19309-14-9
Formula Weight
270.28g/mol
Form
Solid
Description
95% by HPLC
Molecular Formula
C16H14O4
Solubility
DMSO or EtOH
Quantity
2 mg
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Sigma Aldrich Fine Chemicals Biosciences Cardamonin >=98% (HPLC) | 19309-14-9 | MFCD00238554 | 5MG | -- | ₹ 18,861.77 | ||
Sigma Aldrich Fine Chemicals Biosciences Cardamonin >=98% (HPLC) | 19309-14-9 | MFCD00238554 | 25MG | -- | ₹ 73,303.96 | ||
Medchemexpress LLC HY-N1378 5mg Medchemexpress, (E)-Cardamonin CAS:19309-14-9 Purity:>98% | -- | -- | ||
19309-14-9 | Cardamonin | -- | ₹ 1,246.00 - ₹ 1,33,945.00 |
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Description
- Cardamonin, a known 2',4'-dihydroxy-6'-methoxychalcone, was identified as an inhibitor of melanocyte differentiation, among many other pharmacology activities
- Cardamonin promoted degradation of intracellular β-catenin while suppressing melanogenesis by down-regulating the expression of MITF and tyrosinase, resulting in decreased melanin content
- Furthermore, it was found that cardamonin promoted the degradation of β-catenin through a GSK-3β-independent mechanism, which suggested that Siah-dependent pathway and/or a PKCα-dependent pathway, rather than a GSK-3β-dependent pathway, may mediate intracellularb-catenin degradation by cardamonin.