74-051-0

Tocris Bioscience™ TWS 119

Manufacturer: Tocris Bioscience™

CAS Number: 601514-19-6

Select a Size

Pack Size SKU Availability Price
Each of 1 74-051-0-Each-of-1 In Stock ₹ 30,883.00

74-051-0 - Each of 1

₹ 30,883.00

In Stock

Quantity

1

Base Price: ₹ 30,883.00

GST (18%): ₹ 5,558.94

Total Price: ₹ 36,441.94

Chemical Name or Material

3-[[6-(3-Aminophenyl)-7 H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol

Quantity

10 mg

Molecular Formula

C18H14N4O2

CAS

601514-19-6

Target

GSK-3 Inhibitors

Purity

0.97

Related Products

Img

Fischer Scientific

7237132

Potent and selective MTH1 inhibitor...

Img

Tocris Bioscience™

76-371-0

--

Img

Fischer Scientific

80-311-0

--

Img

Fischer Scientific

73-091-0

--

Img

Fischer Scientific

7182961

Potent and selective positive allos...

Img

Fischer Scientific

75-111-0

--

Img

Fischer Scientific

75-115-0

--

Img

Fischer Scientific

80-315-0

--

Description

  • TWS 119 is a potent inhibitor of glycogen synthase kinase-3β (IC50 = 30 nM)
  • TWS 119 inhibits both GSK3α and GSK3β in vitro (IC50 = 88 nM and 410 nM, respectively)
  • TWS 119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells at 400 nM
  • TWS 119 enhances the proliferation and survival of γδ T-cells, and induces differentiation of CD8+ T cells towards a stem cell-like memory T cell phenotype at 2.5 μM.

SAFETY INFORMATION

  • Recommended Storage : Store at +4°C