SML1933

TP-472N

≥98% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 2080306-24-5

Synonym(S): 1-[8-[2-(Cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]-ethanone

Select a Size

Pack Size SKU Availability Price
5 MG SML1933-5-MG In Stock ₹ 16,383.60

SML1933 - 5 MG

₹ 16,383.60

In Stock

Quantity

1

Base Price: ₹ 16,383.60

GST (18%): ₹ 2,949.048

Total Price: ₹ 19,332.648

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C)C1=CC(C2=CC=CC=C2OCC3CC3)=C4N=CC=CN41

Other Options

Image Product Name Manufacturer Price Range
Sigma Aldrich Fine Chemicals Biosciences TP-472N >=98% (HPLC) | 2080306-24-5 | MFCD30720894 | 5MG
-- ₹ 19,297.87
2080306-24-5 | Ethanone, 1-[8-[2-(cyclopropylmethoxy)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]-
-- --

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Description

  • Biochem/physiol Actions: TP-472N is a negative control probe for TP-472. TP-472 is a selective probe for bromodomain-containing proteins BRD9 and BRD7. The BRD9/7 probe was developed out of a collaborative effort by Takeda and the SGC, and is of a different chemotype from BRD9/7 probes previously available. TP-472 has a KD value of 33nM for BRD9 and 340nM for BRD7 by ITC, is >30 fold selective for BRD9 over all other bromodomain family members except BRD7, and is suitable for in vivo applications. The negative control TP-472N is inactive against other bromodomains (>20μM against BRD9). For full characterization details of TP-472 and TP-472N, please visit the TP-472 probe summary on the Structural Genomics Consortium (SGC) website.TP-472, the active BRD9/7 probe, is available from Sigma. To learn more about and purchase TP-472, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
  • Features and Benefits: TP-472N is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable