23-980-35MG

MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum

Manufacturer: Fischer Scientific

CAS Number: 4449-51-8

Select a Size

Pack Size SKU Availability Price
Each of 1 23-980-35MG-Each-of-1 In Stock ₹ 50,092.76

23-980-35MG - Each of 1

₹ 50,092.76

In Stock

Quantity

1

Base Price: ₹ 50,092.76

GST (18%): ₹ 9,016.697

Total Price: ₹ 59,109.457

Color

Off-white

CAS

4449-51-8

Formula Weight

411.6g/mol

Content And Storage

Protect from light

Quantity

5 mg

Target Proteins

Hh signaling in Shh-light2 assay

Molecular Formula

C27H41NO2

Solubility

DMSO, EtOH, or DMF

Form

Solid

Purity

97% by HPLC

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Description

  • A cell-permeable steroidal alkaloid and cholesterol mimic that displays both teratogenic and antitumor activities
  • It disrupts cholesterol bio-synthesis and specifically antagonizes shh (Sonic Hedgehog) signaling pathway through direct interaction with Smo (smoothened), a distant relative of G-protein-coupled receptors
  • A valuable tool for studying the involvement of shh signaling in the development of various tumors
  • Tomatidine (Cat
  • No
  • 614350) can be used as a negative control
  • Also available as a 10mm solution in Ethanol (Cat
  • No
  • 239806).