01-670-391

Transferrin Receptor Monoclonal Antibody (ICO-92), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-391-Each-of-1 In Stock ₹ 45,345.50

01-670-391 - Each of 1

₹ 45,345.50

In Stock

Quantity

1

Base Price: ₹ 45,345.50

GST (18%): ₹ 8,162.19

Total Price: ₹ 53,507.69

Antigen

Transferrin Receptor

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.2% gelatin, 0.5% saccharose and 0.1% sodium azide; pH 7.4

Gene Accession No.

P02786

Gene Symbols

TFRC

Immunogen

Transferrin receptor on activated T-B-cells.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

ICO-92

Conjugate

Unconjugated

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7037

Content And Storage

4°C short term, -80°C long term

Form

Liquid

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Description

  • MA1-7657 detects Transferrin receptor from human samples
  • MA1-7657 has been successfully used in flow cytometry procedures
  • The MA1-7657 immunogen is a Transferrin receptor on activated T-B-cells
  • Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.