01-671-874
INSR Monoclonal Antibody (18-44), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-671-874-Each-of-1 | In Stock | ₹ 59,185.00 |
01-671-874 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,185.00
GST (18%): ₹ 10,653.30
Total Price: ₹ 69,838.30
Antigen
INSR
Classification
Monoclonal
Concentration
0.41 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
P06213
Gene Symbols
INSR
Immunogen
human placental insulin receptor.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Applications
Immunoprecipitation, Western Blot
Clone
18-44
Conjugate
Unconjugated
Gene
INSR
Gene Alias
4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3643
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-10865 detects Insulin Receptor from human samples
- Low cross-reactivity with bovine and rabbit samples
- MA1-10865 has been successfully used in Western blot and immunoprecipitation applications
- The MA1-10865 immunogen is human placental insulin receptor
- INSR is a receptor tyrosine kinase
- Binding of insulin to the extracellular domain of INSR stimulates glucose uptake
- INSR and IGF-1 receptors share major structural and functional similarity
- The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR
- In humans, the INSR gene is located on chromosome 19
- Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.