01-670-532

GPX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-670-532-Each-of-1 In Stock ₹ 49,083.50

01-670-532 - Each of 1

₹ 49,083.50

In Stock

Quantity

1

Base Price: ₹ 49,083.50

GST (18%): ₹ 8,835.03

Total Price: ₹ 57,918.53

Antigen

GPX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GPX1

Gene Alias

AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1

Host Species

Sheep

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with no preservative

Gene Accession No.

P04041, P07203

Gene Symbols

GPX1

Immunogen

Synthetic peptide corresponding to residues R(175) R Y S R R F Q T I D I E P D I E A L L(194) of human glutathione peroxidase 1 ( GPx-1).

Regulatory Status

RUO

Gene ID (Entrez)

24404, 2876

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • Reconstitute in 100 μL of sterile water
  • Centrifuge to remove any insoluble material
  • After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent
  • Avoid repetitive freeze/thaw cycles
  • Glycerol (1:1) may be added for an additional stability
  • Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione
  • There are several isoforms which differ in their primary structure and localization
  • The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered
  • GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract
  • Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation
  • Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine
  • All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site
  • Order Info Not available outside US