01-670-942

COX1 Mouse anti-Human, Clone: AS70, Invitrogen™

Manufacturer: Qorpak

Select a Size

Pack Size SKU Availability Price
Case of 12 01-670-942-Case-of-12 In Stock ₹ 4,798.88

01-670-942 - Case of 12

₹ 4,798.88

In Stock

Quantity

1

Base Price: ₹ 4,798.88

GST (18%): ₹ 863.798

Total Price: ₹ 5,662.678

Antigen

COX1

Classification

Monoclonal

Concentration

1 mg/mL

Gene

PTGS1

Gene Alias

COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS, PTGS1

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

5742

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Clone

AS70

Conjugate

Unconjugated

Gene Accession No.

P23219

Gene Symbols

PTGS1

Immunogen

Human recombit COX1 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • This antibody does not cross-react with human COX2
  • PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase
  • There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution
  • This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin
  • PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis
  • Alternative splicing of this gene generates two transcript variants
  • The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.