01-674-107

MAGI3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-107-Each-of-1 In Stock ₹ 46,502.50

01-674-107 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MAGI3

Classification

Polyclonal

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

Q5TCQ9

Gene Symbols

MAGI3

Immunogen

Recombinant protein corresponding to PDZ domain 4-5 of MAGI-3.

Quantity

250 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

MAGI3

Gene Alias

4732496O19Rik; 6530407C02Rik; AA407180; AI120132; dJ730K3.2; GKWW domain; KIAA1634; Magi3; MAGI-3; membrane associated guanylate kinase, WW and PDZ domain containing 3; membrane-associated guanylate kinase inverted 3; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; membrane-associated guanylate kinase-related (MAGI-3); membrane-associated guanylate kinase-related 3; mKIAA1634; PDZ 4-5; RP4-730K3.1; scaffolding protein SLIPR; scaffolding-like protein; Slipr

Host Species

Sheep

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

260425

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases
  • These guanylate kinases are localized to epithelial cell tight junctions
  • MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB)
  • MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival
  • MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is them followed by 5 PDZ domains.