BID Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-600-Each-of-1 | In Stock | ₹ 46,502.50 |
01-674-600 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
BID
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BID
Gene Alias
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
637
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P55957
Gene Symbols
BID
Immunogen
Synthetic peptide corresponding to the C terminus amino acids TYVRSLARNGMD.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000
- BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
- Bid is a member of the BCL-2 family of cell death regulators
- BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
- BID is also a pro-apoptotic member of the Bcl 2 family
- BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
- Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
- BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.