01-674-649

Livin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-649-Each-of-1 In Stock ₹ 46,502.50

01-674-649 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Livin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BIRC7

Gene Alias

baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing 7; baculoviral IAP repeat-containing 7 (livin); baculoviral IAP repeat-containing protein 7; Baculoviral IAP repeat-containing protein 7 30 kDa subunit; Baculoviral IAP repeat-containing protein 7 30kDa subunit; Birc7; E130019N06; KIAP; Kidney inhibitor of apoptosis protein; LIVIN; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; MLIAP; ML-IAP; RGD1562883; RING finger protein 50; RING-type E3 ubiquitin transferase BIRC7; RNF50; RP11-261N11.7; Truncated livin; UNQ5800/PRO19607/PRO21344

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

79444

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96CA5

Gene Symbols

BIRC7

Immunogen

Synthetic peptide corresponding to the C terminus amino acids RAPVRSRVRT

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000
  • The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli
  • All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity
  • Recently, it has been identified that a novel human inhibitor of apoptosis protein (IAP) family member termed Livin or ML-IAP, which contains a single baculoviral IAP repeat (BIR) domain and a COOH-terminal RING finger domain
  • Livin gene has two splicing variants that contain open reading frames of 298 and 280 amino acids and both contained a single copy of baculovirus IAP repeat (BIR) and RING domain
  • Both of the isoforms inhibit TNFa induced apoptosis in Jurkat cells
  • Livin expression is low in adult tissues
  • It is relatively expressed at a higher level in developmental tissues and in many cancer cells.