01-674-793
Farnesyl Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-793-Each-of-1 | In Stock | ₹ 54,023.00 |
01-674-793 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,023.00
GST (18%): ₹ 9,724.14
Total Price: ₹ 63,747.14
Antigen
Farnesyl
Classification
Polyclonal
Conjugate
Unconjugated
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Target Species
Chemical
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry
Concentration
1 mg/mL
Formulation
PBS with 0.08% sodium azide
Immunogen
Farnesyl cysteine conjugated to KLH
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Target Molecule
Chemical
Related Products
Description
- Isoprenylation/methylation is an important posttranslational lipid modification: the covalent addition of a 15 carbon farnesyl or a 20-carbon geranylgeranyl group to the C-terminus of a protein results in a substantial increase in hydrophobicity
- All known G proteins are modified in this way, making the pathway of central interest for an understanding of signal transduction
- From nematode to human, many eukaryotic proteins are reported to be isoprenylated
- Known prenylated prtoteins include fungal mating factors, nuclear lamins, Ras and Ras-related GTP-binding proteins (G proteins), and the subunits of trimeric G proteins, protein kinases and at least one viral prtoein
- Prenylation promotes membrane interactions of most of these proteins, which is not surprising given the hydrophobicity of the lipids involved
- In addition, prenylation appears to play a major role in several protein-protein interaction.