01-674-848
GPR68 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-848-Each-of-1 | In Stock | ₹ 52,777.00 |
01-674-848 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,777.00
GST (18%): ₹ 9,499.86
Total Price: ₹ 62,276.86
Antigen
GPR68
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GPR68
Gene Alias
BB131428; Brgr1; Brgrb; G protein-coupled receptor 68; GPR12A; Gpr68; G-protein coupled receptor 68; Ogr1; OGR-1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
8111
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry, Neutralization, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.08% sodium azide
Gene Accession No.
Q15743
Gene Symbols
GPR68
Immunogen
Recombinant protein corresponding to human OGR1 (GPR68) protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Western blot should be visualized using a high sensitivity secondary/substrate system (i.e SuperSignal West Femto Maximum Sensitivity Substrate)
- A suggested positive control for this product is OGR1 transfected cell lysate
- GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis
- It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone
- GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization
- The receptor is almost silent at pH 7.8 but fully activated at pH 6.8
- Also found to serve as a tumor suppressor in prostate cancer
- Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.