01-675-003
ICAM-3 Monoclonal Antibody (MEM-04), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-003-Each-of-1 | In Stock | ₹ 25,409.50 |
01-675-003 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,409.50
GST (18%): ₹ 4,573.71
Total Price: ₹ 29,983.21
Antigen
ICAM-3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
P32942
Gene Symbols
ICAM3
Immunogen
Leukocytes from a patient suffering from LGL type leukemia.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin)
Clone
MEM-04
Conjugate
Unconjugated
Gene
ICAM3
Gene Alias
CD50; CDw50; ICAM3; ICAM-3; ICAM-R; Intercellular adhesion molecule 3; intercellular adhesion molecule-3
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3385
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 μm filter sterilized
- Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test
- Functional Application: Blocking
- CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin
- Besides functioning as an adhesive molecule that mediates e.g
- the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation
- ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.