CENPE Monoclonal Antibody (1H12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-178-Each-of-1 | In Stock | ₹ 81,435.00 |
01-675-178 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 81,435.00
GST (18%): ₹ 14,658.30
Total Price: ₹ 96,093.30
Antigen
CENPE
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
Q02224
Gene Symbols
CENPE
Immunogen
Recombinant full length CENP-E protein (human) from SP2/0 cells
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG κ
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
1H12
Conjugate
Unconjugated
Gene
CENPE
Gene Alias
312kDa; AU019344; BC049989; C530022J18; Cenpe; CENP-E; centromere autoantigen E; Centromere autoantigen E (312kD); centromere protein E; centromere protein E, 312kDa; centromere-associated protein E; centromeric protein E; KIF10; kinesin 10; kinesin family member 10; kinesin superfamily protein 10; Kinesin-7; Kinesin-related protein CENPE; MCPH13; Motor domain of KIF10; N-7 kinesin; PPP1R61; protein phosphatase 1, regulatory subunit 61
Host Species
Mouse
Purification Method
Ion-exchange chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1062
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This target has a predicted molecular weight of 312 kDa and is only suitable for Western blot if IP is performed first
- 14-3-3 sigma (stratifin, SFN, epithelial cell marker protein 1) is a member of a highly conserved family of 14-3-3 proteins that are present in all eukaryotic organisms
- There are 7 known mammalian 14-3-3 isoforms epsilon, beta, zeta, gamma, theta, tau and they play important roles in many biological activities by binding to and altering the subcellular localization and/or stability of key molecules in various signaling cascades
- 14-3-3 sigma was originally characterized as a human mammary epithelium marker and later rediscovered as an important molecule for cell cycle checkpoint regulation
- Recently it has been reported that 14-3-3 sigma may serve as a prognosis marker predicting survival of pancreatic cancer patient treatment
- 14-3-3 sigmais the only 14-3-3 isoform induced by the tumor suppressor protein p53, in response to <FONT face=Symbol>g</FONT>-irradiation and other DNA-damaging agents
- 14-3-3 sigmais a p53-regulated inhibitor of G2/M progression and acts as a tumor suppressor gene that is inactivated by methylation of its 5' CpG islands in epithelial tumor cells
- Two isoforms of human 14-3-3 sigma are produced by alternative splicing.