01-675-719

SMAD1/SMAD5/SMAD9 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-719-Each-of-1 In Stock ₹ 46,502.50

01-675-719 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SMAD1/SMAD5/SMAD9

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD1

Gene Alias

1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog 9; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; MADH1; MADH5; MADH6; Madh8; Madh9; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic homolog 9; mothers against decapentaplegic, drosophila, homolog of, 5; Mothers against decapentaplegic, drosophila, homolog of, 9; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers against DPP homolog 9; mothers-against-DPP-related 1; Msmad5; MusMLP; PPH2; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD 9; SMAD family member 1; SMAD family member 5; SMAD family member 9; SMAD, mothers against DPP h

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

17125, 17129, 25671, 4086, 4090, 4093, 55994, 59328, 85435

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O15198, O54835, P70340, P97454, P97588, Q15797, Q99717, Q9JIW5, Q9R1V3

Gene Symbols

SMAD1, Smad5, SMAD9

Immunogen

Synthetic peptides corresponding to residues 18-32 L(18) G W K Q G D E E E K W A E K(32) and S(315) N V N R N S T I E N T R R H(329) of human SMAD1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with chicken, chimpanzee, invertabrates, mammals, porcine, xenopus and zebrafish samples based on sequence homology
  • The protein encoded by SMAD1/SMAD5/SMAD8/SMAD9 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C
  • elegans gene Sma
  • SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways
  • This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses
  • In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase
  • The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation
  • This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation
  • Alternatively spliced transcript variants encoding the same protein have been observed.