01-676-052

DAXX Monoclonal Antibody (DAXX-01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-052-Each-of-1 In Stock ₹ 41,385.00

01-676-052 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

DAXX

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

Q9UER7

Gene Symbols

DAXX

Immunogen

Recombinant C-terminal part (aa 558-740) of human Daxx.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

DAXX-01

Conjugate

Unconjugated

Gene

DAXX

Gene Alias

BING2; CENP-C binding protein; DADB-159G18.9; DAP6; Daxx; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246; SMIM40; Unknown (protein for MGC:138055)

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1616

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm
  • It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1
  • In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors
  • Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli
  • This protein also associates with centromeres in G2 phase
  • In the cytoplasm, the encoded protein may function to regulate apoptosis
  • The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination
  • Alternative splicing results in multiple transcript variants.