01-676-083

NTAL Monoclonal Antibody (NAP-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-083-Each-of-1 In Stock ₹ 41,385.00

01-676-083 - Each of 1

₹ 41,385.00

In Stock

Quantity

1

Base Price: ₹ 41,385.00

GST (18%): ₹ 7,449.30

Total Price: ₹ 48,834.30

Antigen

NTAL

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

Q9GZY6

Gene Symbols

LAT2

Immunogen

Peptide corresponding to aa 196-212 of human NTAL, coupled to KLH.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

NAP-03

Conjugate

Unconjugated

Gene

LAT2

Gene Alias

AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7462

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • This antibody will not cross-react with mouse
  • Western Blot: Incubation 60 min; non-reducing conditions, 12% separating SDS-PAGE gel
  • NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages
  • It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells
  • However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.