Transferrin Receptor Monoclonal Antibody (MEM-75), Biotin, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-239-Each-of-1 | In Stock | ₹ 50,196.00 |
01-676-239 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,196.00
GST (18%): ₹ 9,035.28
Total Price: ₹ 59,231.28
Antigen
Transferrin Receptor
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P02786
Gene Symbols
TFRC
Immunogen
Pre-B cell line NALM-6.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone
MEM-75
Conjugate
Biotin
Gene
TFRC
Gene Alias
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7037
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
- Endosomal acidification leads to iron release
- The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
- Transferrin receptor is necessary for development of erythrocytes and the nervous system
- Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.