14-090-995

CD90 (Thy-1) Monoclonal Antibody (eBio5E10 (5E10)), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 14-090-995-Each-of-1 In Stock ₹ 3,06,605.00

14-090-995 - Each of 1

₹ 3,06,605.00

In Stock

Quantity

1

Base Price: ₹ 3,06,605.00

GST (18%): ₹ 55,188.90

Total Price: ₹ 3,61,793.90

Antigen

CD90 (Thy-1)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P04216

Gene Symbols

Thy1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7070

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

eBio5E10 (5E10)

Conjugate

Unconjugated

Gene

Thy1

Gene Alias

CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen

Host Species

Mouse

Quantity

10 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The eBio5E10 monoclonal antibody reacts with human CD90, also known as Thy-1 (thymus cell antigen-1)
  • CD90 is a 25-35 kD receptor expressed on thymocytes, CD34+ prothymocytes, hematopoietic stem cells, neurons, a small subset of human fetal liver cells, cord blood cells, and bone marrow cells
  • CD90 is expressed on a subset of immature, CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+
  • The CD90+CD34+ population is enriched for cells capable of long-term culture
  • CD90 is involved in regulation of adhesion and signal transduction by T cells
  • Applications Reported: This eBio5E10 (5E10) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistology staining of frozen tissue sections
  • Applications Tested: This eBio5E10 (5E10) antibody has been tested by flow cytometric analysis of human erythroleukemia (HEL) cells
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family
  • CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts
  • CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain
  • CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons
  • Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor
  • Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.