14-101-995
CD101 Monoclonal Antibody (BB27), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-101-995-Each-of-1 | In Stock | ₹ 3,08,830.00 |
14-101-995 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 3,08,830.00
GST (18%): ₹ 55,589.40
Total Price: ₹ 3,64,419.40
Antigen
CD101
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q93033
Gene Symbols
CD101
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9398
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone
BB27
Conjugate
Unconjugated
Gene
CD101
Gene Alias
Cd101; CD101 antigen; CD101 molecule; cell surface glycoprotein V7; EWI immunoglobulin subfamily member EWI-101; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; Gm1016; Gm734; IGSF2; Immunoglobulin superfamily member 2; immunoglobulin superfamily, member 2; leukocyte surface protein; RP11-27K13.2; V7
Host Species
Mouse
Quantity
10 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- The MAb BB27 reacts to human CD101 also known as V7 antigen, a member of the Ig superfamily
- CD101 is a disulfide linked homodimer of unknown function
- Expression of CD101 is found on monocytes, granulocytes and dendritic cells (Langerhan-like cells HLA-DR, CD1a, CD1c)
- In addition expression on T lymphocytes is important for cell activation
- CD101+ CD28+ cells are very responsive to CD28 signaling
- In combination with anti-CD28 or suboptimal levels of anti-CD3, anti-CD101 can increase proliferation thereby suggesting an activating role
- The MAb BB27 has been shown to inhibit the T cell reactivity in allogeneic and antigen-specific mixed DC-T cell cultures
- Recently it has been demonstrated that mouse CD101 is found on a subpopulation of regulatory T cells (CD4, CD25, Foxp3 positive) that have high suppressor activity
- Expression of CD101 on human PBMCs shows staining of about 30% of the Foxp3 positive cells
- Studies have not confirmed higher suppressor activity in the human CD101 population
- CD101 also known as V7 antigen, a member of the Ig superfamily
- CD101 is a disulfide linked homodimer of unknown function
- Expression of CD101 is found on monocytes, granulocytes and dendritic cells (Langerhan-like cells HLA-DR, CD1a, CD1c)
- In addition expression on T lymphocytes is important for cell activation
- CD101+ CD28+ cells are very responsive to CD28 signaling
- In combination with anti-CD28 or suboptimal levels of anti-CD3, anti-CD101 can increase proliferation thereby suggesting an activating role
- The monoclonal antibody BB27 has been shown to inhibit the T cell reactivity in allogeneic and antigen-specific mixed DC-T cell cultures
- Recently it has been demonstrated that mouse CD101 is found on a subpopulation of regulatory T cells (CD4, CD25, Foxp3 positive) that have high suppressor activity
- Expression of CD101 on human PBMCs shows staining of about 30% of the Foxp3 positive cells
- Studies have not confirmed higher suppressor activity in the human CD101 population.