CD144 (VE-cadherin) Monoclonal Antibody (16B1), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-144-937-Each-of-1 | In Stock | ₹ 1,22,642.00 |
14-144-937 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,642.00
GST (18%): ₹ 22,075.56
Total Price: ₹ 1,44,717.56
Antigen
CD144 (VE-cadherin)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P33151
Gene Symbols
CDH5
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1003
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
16B1
Conjugate
Unconjugated
Gene
CDH5
Gene Alias
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Description: The 16B1 antibody reacts with human CD144, also known as VE-cadherin and cadherin-5
- The cadherin family of receptors, which are calcium-dependent adhesion molecules, is known to be involved in homophilic cell interactions
- VE-cadherin, which is 140 kDa, is localized at the intercellular boundaries of endothelial cells in blood and lymphatic vessels in several tissues
- It is thought to play a role in vascular permeability and remodeling
- Applications Reported: This 16B1 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), microscopy, and immunocytochemistry without fixation
- Applications Tested: This 16B1 antibody has been tested by immunoblotting Human Umbilical Vein Endothelial Cell (HUVEC) lysates
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer
- VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
- Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions
- An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.