14223782
P-Cadherin Monoclonal Antibody (CSTEM29), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14223782-Each-of-1 | In Stock | ₹ 29,160.85 |
14223782 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,160.85
GST (18%): ₹ 5,248.953
Total Price: ₹ 34,409.803
Antigen
P-Cadherin
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P10287, P22223
Gene Symbols
Cdh3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1001, 12560
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
CSTEM29
Conjugate
Unconjugated
Gene
Cdh3
Gene Alias
AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
Host Species
Mouse
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- This monoclonal antibody CSTEM29 reacts with human P-Cadherin, also known as Cadherin-3
- Applications Reported: This CSTEM29 antibody has been reported for use in flow cytometric analysis and immunoblot
- Applications Tested: This CSTEM29 antibody has been tested by flow cytometric analysis of normal human induced pluripotent stem cells, and for western blot
- For flow cytometry, this may be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- For western blot, this can be used at less than or equal to 10 μg/mL
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily
- Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin
- Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation
- P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium
- P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle
- Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas
- Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.