COX4 Monoclonal Antibody (IB52C31H10), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-977-582-Each-of-1 | In Stock | ₹ 33,820.00 |
14-977-582 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 33,820.00
GST (18%): ₹ 6,087.60
Total Price: ₹ 39,907.60
Antigen
COX4
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P10888, P13073, P19783
Gene Symbols
COX4I1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12857, 1327, 29445
Content And Storage
4° C
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
IB52C31H10
Conjugate
Unconjugated
Gene
COX4I1
Gene Alias
AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER membrane protein complex subunit 8; FAM158B; family with sequence similarity 158, member B; FLJ23483; hypothetical protein MGC73355; IV-1; mg:bb02d03; MGC72016; Neighbor of COX4; NOC4; Protein FAM158B; XELAEV_18024950mg; zgc:110058; zgc:73355
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The IB52C31H10 MAb recognizes human COX IV
- COX IV, also known as cytochrome c oxidase (COX) or Complex IV, is the terminal complex of the electron transport chain
- COX IV is encoded by nuclear DNA and localized to the inner mitochondrial membrane
- COX IV functions in energy metabolism and shuttles electrons from cytochrome c to oxygen
- Dysfunction in COX IV is associated with increased production of reactive oxygen species and cellular toxicity
- Genetic defects in COX IV results in severe, often fatal metabolic disorders that primarily affect tissues with high energy demands such as heart, brain, and muscle
- Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain
- It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane
- The complex consists of 13 mitochondrial- and nuclear-encoded subunits
- The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex
- COX4 (COX4I1) is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.