T-bet Monoclonal Antibody (eBio4B10 (4B10)), PE-Cyanine5, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 15-582-582-Each-of-1 | In Stock | ₹ 42,008.00 |
15-582-582 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,008.00
GST (18%): ₹ 7,561.44
Total Price: ₹ 49,569.44
Antigen
T-bet
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9JKD8, Q9UL17
Gene Symbols
Tbx21
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
30009, 57765, 694044
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio4B10 (4B10)
Conjugate
PE-Cyanine5
Gene
Tbx21
Gene Alias
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1 κ
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Description
- T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain
- It controls the expression of the TH1 cytokine, interferon-gamma
- Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development
- T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17
- T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression
- Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.