CD210 (IL-10R) Monoclonal Antibody (1B1.3a), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 16-210-185-Each | In Stock | ₹ 29,071.85 |
16-210-185 - Each
In Stock
Quantity
1
Base Price: ₹ 29,071.85
GST (18%): ₹ 5,232.933
Total Price: ₹ 34,304.783
Antigen
CD210 (IL-10R)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
Q61727
Gene Symbols
Il10ra
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16154
Content And Storage
4° C
Form
Liquid
Applications
Functional Assay
Clone
1B1.3a
Conjugate
Functional Grade
Gene
Il10ra
Gene Alias
AW553859; CD210; CD210a; CDw210; CDW210A; CDW210B; CRF2-4; CRFB4; D21S58; D21S66; HIL-10R; I10R; I10R1; il-10 receptor; il-10 receptor antagonist; IL-10 receptor subunit alpha; IL10R; IL-10R alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10R2; Il10ra; IL-10RA; interleukin 10 receptor subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha; mIL-10R
Host Species
Rat
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Description: The 1B1.3A monoclonal antibody reacts with mouse CD210, which is also known as the IL-10 receptor
- CD210 is a member of the interferon receptor-like family that is expressed on a variety of hematopoietic cells, including thymocytes, T cells, B cells, NK cells, monocytes, and macrophages
- Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation
- The 1B1.3A antibody has been reported to have neutralizing activity
- Applications Reported: The 1B1.3A antibody has been reported for use in functional assays
- Storage and handling: Use in a sterile environment
- Filtration: 0.2 μm post-manufacturing filtered
- Purity: Greater than 90%, as determined by SDS-PAGE
- Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
- Aggregation: Less than 10%, as determined by HPLC
- The protein encoded by this gene is a receptor for interleukin 10
- This protein is structurally related to interferon receptors
- It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines
- This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway
- Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases
- Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.