Lymphotoxin beta Receptor Monoclonal Antibody (eBio3C8 (3C8)), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 16-567-138-Each | In Stock | ₹ 2,10,809.85 |
16-567-138 - Each
In Stock
Quantity
1
Base Price: ₹ 2,10,809.85
GST (18%): ₹ 37,945.773
Total Price: ₹ 2,48,755.623
Antigen
Lymphotoxin beta Receptor
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P50284
Gene Symbols
Ltbr
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17000
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Functional Assay
Clone
eBio3C8 (3C8)
Conjugate
Functional Grade
Gene
Ltbr
Gene Alias
AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III
Host Species
Rat
Quantity
5 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The antibody reacts with mouse lymphotoxin-beta receptor (LTBR)
- Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes
- The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxinalpha and lymphotoxin beta
- This LT alpha/LTbeta heterotrimer (LT alpha 1/beta 2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120 alpha) or TNFR2 (CD120 beta)
- LTBR is expressed by day 7 embryos, so it has been speculated that the LT alpha/LT beta receptor system may also have some function in early embryogenesis
- The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors
- It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes
- The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta)
- The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells
- Activation of the encoded protein can trigger apoptosis.