200020040

CD141 Monoclonal Antibody (LS17-9), Brilliant Ultra Violet™ 805, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD141

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide, pH 7.2

Gene Alias

AHUS6, AI385582, BDCA3, BDCA-3, CD141, CD141 antigen, DC141, fetomodulin, sCD141, snoRNA MBII-339, soluble CD141, THBD, THPH12, THRM, thrombomdulin, thrombomodulin, thrombomodulin precursor, TM

Gene Symbols

THBD

Primary or Secondary

Primary

Content And Storage

4°, C, store in dark, DO NOT FREEZE!

Clone

LS17-9

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 805

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P15306

Gene ID (Entrez)

21824

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Gene

THBD

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Description

  • Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112
  • Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein
  • Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells
  • Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.