Hemoglobin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Hemoglobin
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Canine, Human, Non-human Primate, Porcine
Gene Accession No.
P02067, P68871, P69905
Gene ID (Entrez)
3039, 3043, 407066
Immunogen
Native Simian HB protein (Accession #P63108;P68223)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
alpha one globin, alpha-1 globin, alpha-1-globin, alpha-2 globin chain, Alpha-globin, ALPHA-GLOBIN GENE, delta globin, Haemoglobin, Hb, HBA1, HbA1c, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols
HBA1, HBB
Isotype
IgG
Purification Method
Protein A
Gene
HBB
Related Products
Description
- The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'
- The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical
- These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions
- Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin
- Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.