Hemoglobin alpha-1 Monoclonal Antibody (C6), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Hemoglobin alpha-1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
alpha one globin, alpha-2 globin chain, Alpha-globin, delta globin, HBA1, HBA2, HBA-T3, HBH, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin subunit alpha 1, hemoglobin, alpha 1
Gene Symbols
HBA1
Isotype
IgG1 κ
Purification Method
Protein A/G
Gene
HBA1
Clone
C6
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Rat
Gene Accession No.
P01946, P69905
Gene ID (Entrez)
25632, 3039
Immunogen
Recombinant Human HBa1 protein, Met1-Arg142 (Accession #P69905)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'
- The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical
- These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions
- Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin
- Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.