200020105

FAP Monoclonal Antibody (D3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

FAP

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

170 kDa melanoma membrane-bound gelatinase, Antiplasmin-cleaving enzyme FAP, soluble form, APCE, Dipeptidyl peptidase FAP, DPPIV, Fap, FAPA, FAPalpha, fibroblast activation protein, fibroblast activation protein alpha, fibroblast activation protein, alpha, gelatine degradation protease FAP, Integral membrane serine protease, post-proline cleaving enzyme, Prolyl endopeptidase FAP, seprase, Serine integral membrane protease, SIMP, Surface-expressed protease

Gene Symbols

FAP

Isotype

IgG2b κ

Purification Method

Protein A/G

Gene

FAP

Clone

D3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

Q12884

Gene ID (Entrez)

100736572, 2191

Immunogen

Recombinant Human FAPa protein, Ile523-Asp760 (Accession #Q12884)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family
  • It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas
  • This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.