200020125

TMPRSS2 Monoclonal Antibody (C1), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

TMPRSS2

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

D16Ertd61e, EC 3.4.219, epitheliasin, FLJ41954, MGC6821, Plasmic transmembrane protein X, PP9284, PRSS10, Serine protease 10, Tmprss2, TMPS2, Transmembrane protease serine 2, Transmembrane protease serine 2 catalytic chain, Transmembrane protease serine 2 non-catalytic chain, transmembrane protease, serine 2

Gene Symbols

TMPRSS2

Isotype

IgG2a κ

Purification Method

Protein A/G

Gene

TMPRSS2

Clone

C1

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

O15393

Gene ID (Entrez)

7113

Immunogen

Recombinant Human TMPRSS2 protein, Ser284-Gly492 (Accession #O15393)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • TMPRSS2 is a protein that belongs to the serine protease family
  • The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain
  • Serine proteases are known to be involved in many physiological and pathological processes
  • Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue
  • The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.