200020148

SERPINF2 Monoclonal Antibody (C3), Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SERPINF2

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

A2AP, AAP, AI747498, alpha 2 antiplasmin, alpha-2-antiplasmin, Alpha-2-AP, alpha-2-PI, Alpha-2-plasmin inhibitor, API, pigment epithelium derived factor, plasmin inhibitor alpha 2, Pli, serine (or cysteine) peptidase inhibitor, clade F, member 2, serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2, serine (or cysteine) proteinase inhibitor, clade F, member 2, Serpimf2, serpin F2, serpin family F member 2, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2, Serpinf2

Gene Symbols

SERPINF2

Isotype

IgG1 κ

Purification Method

Protein A/G

Gene

SERPINF2

Clone

C3

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Porcine

Gene Accession No.

P08697

Gene ID (Entrez)

100525254, 5345

Immunogen

Recombinant Human a2PI protein (Accession #P08697)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

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Description

  • This gene encodes a member of the serpin family of serine protease inhibitors
  • The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins
  • Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway
  • Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis
  • Multiple transcript variants encoding different isoforms have been found for this gene.