200020318

SERPINB4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SERPINB4

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P48594

Gene ID (Entrez)

20248, 6318

Immunogen

Recombinant Mouse SERPINB4 protein, Asn60-Leu222 (Accession #Q9Z2G2)

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Concentration

0.5 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4

Gene Alias

1110001H02Rik, 1110013A16Rik, LEUPIN, Leupin SERPINB4, Peptidase inhibitor 11, PI11, PI-11, protease inhibitor (leucine-serpin), RGD1562868, SCCA1, SCCA2, SCCA-2, SCCA2/SCCA1 fusion protein, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4, serine peptidase inhibitor, clade B, member 3A, serpin B4, serpin family B member 4, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpinb3a, SERPINB4, Sqn5, squamous cell carcinoma antigen 1, squamous cell carcinoma antigen 2

Gene Symbols

Serpinb3a, SERPINB4

Isotype

IgG

Purification Method

Protein A

Gene

SERPINB4

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Description

  • Description SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin
  • It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.