200020225
Aquaporin 4 Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Aquaporin 4
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
Aqp4, AQP-4, aquaporin 4, aquaporin type4, Aquaporin4, aquaporin-4, HMIWC2, Mercurial-insensitive water channel, MGC22454, MIWC, MIWC2, WCH4
Gene Symbols
AQP4
Isotype
IgG2a κ
Purification Method
Protein A/G
Gene
AQP4
Clone
C1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Porcine
Gene Accession No.
P55087
Gene ID (Entrez)
100126277, 361
Immunogen
Recombinant Human AQP4 protein, Cys178-Gly317 (Accession #P55087)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Related Products
Description
- In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers
- Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane
- This function is conserved in animals, plants and bacteria
- Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10
- Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell
- Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.